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The most pronounced antioxidant defense comprises antioxidant enzymes (superoxide dismutase, catalase, glutathione peroxidase, glutathione reductase, etc.) and nonenzymatic antioxidants such as tocopherols, phenolic compounds, carotenoids, ascorbic acids, and Mycosporine-like amino acids (MAAs)

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reported that the expression level of asparagine synthetase (ASNS) in breast cancer is closely related to metastatic recurrence and that inhibition of ASNS or restriction of dietary Asn can reduce tumor metastasis