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In osteoblasts lacking ER-66, the overexpression of GPER and ER-36 can significantly increase OPG expression, further enhancing bone-protective effects [143]
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In our model the computed value of GSH transport out of the cell (Table 4) is V cGSHb = 1152 and the rates of Cys, Gly, and Glut import are also high (Table 4), although we assume that 10% per hour of the amino acids in the blood are lost to non-liver cells and an additional 25% of Cys is lost by conversion to cystine
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10.1126/sciadv.adr8243 200 HuangH.XuH.LuoQ.HeJ.LiM.ChenH.et al
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