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Female db/+ and db/db (BKS.CgDock7m / Leprdb/J) mice (5-wk-old at arrival and 12-week-old at study start) were obtained from Charles River (Calco, Italy) and housed in a controlled environment (12:12-h light-dark cycle, 23 2C, humidity: 50 10%)

[PubMed | ClinicalTrials.gov | DOI] Talk to Our Team Have specific questions about retatrutide and ibuprofen NSAIDs interaction

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These findings underscore its potential as a senolytic agent with research applications in degenerative diseases, dermatology, and regenerative medicine