C., Tang Z
One of them, bardoxolone methyl (BARD, CDDO-Me, RTA402) is in the late stages of clinical trials for several conditions related to advanced chronic kidney disease including Alport syndrome and an autosomal dominant polycystic kidney disease and to pulmonary arterial hypertension (PAH)
It also helps regenerate other antioxidants, including vitamins C and E, supports normal immune function, and plays an important role in the liver's natural detoxification processes
The physiological landscape of Long COVID, ME/CFS, and related dysautonomias is heavily characterized by a profound, unyielding state of oxidative stress
To transform amaranth from an underused resource into a resilient, high-value crop, the field requires sustained research, innovative technology, and rigorous, systematic evaluation (Bansal and Kaur, 2025