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Vuksic T, Zoricic I, Brcic L, Sever M, Klicek R, Radic B, et al
The NAD+-dependent deacetylase SIRT1 modulates CLOCK-mediated chromatin remodeling and [PMID: 18662547] Laboratory literature summary: The NAD+-dependent deacetylase SIRT1 modulates CLOCK-mediated chromatin remodeling and circadian control
Abstract Background: Vitamin B12 is essential for neurological function, red blood cell formation, and DNA synthesis
Observations are model-dependent and exploratory
Since it does not affect hormone levels, insulin sensitivity, or appetite regulation, there is no rebound effect from discontinuation
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