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Safety profile in PIONEER trials: Nausea: 11% to 20% (dose-dependent) Diarrhea: 8% to 11% Vomiting: 5% to 9% Discontinuation due to GI side effects: 4% to 7% The side effect rates are lower than injectable semaglutide at weight-loss doses, likely because the systemic exposure is lower
Increased proportions of Bifidobacterium and the Lactobacillus group and loss of butyrate-producing bacteria in inflammatory bowel disease
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Fairbanks School of Public Health at IU Indianapolis for speaking with us about this
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