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Progress in Lipid Research 29: 107-140.CrossRefGoogle ScholarPubMed NOUBOUKPO, K.E., TONA, K., AGBONON, A., GBEASSOR, M., BUYSE, J
Figure 1 2 MASLDs pathophysiology and current treatment MASLD is characterized by an abnormal accumulation of lipids in hepatocytes, commonly occurring in the context of obesity, insulin resistance, and T2DM-key features of metabolic syndrome that substantially affect patient quality of life and long-term prognosis ( The complex pathophysiology of MASLD calls for integrated, multi-faceted therapeutic regimens and improved diagnostic tools to enhance clinical outcomes
Currently available anti-obesity medications have shown a modest weight reduction of approximately 5% compared to a placebo when used over the long term
The cooking method is just as important as the food choice for optimal health benefits
In metabolic syndrome, GLP-1s decrease visceral fat and cardiometabolic risk, which may indirectly improve fertility outcomes by normalizing menstrual patterns and endometrial receptivity
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