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The titration process for both medications is designed to minimize these side effects
In the SURMOUNT trials for weight management, participants achieved substantial weight loss, with some individuals losing 1520% of their body weight over the study period, which may indirectly benefit liver health
The absence of dry mouth from formal adverse effect profiles does not definitively exclude the possibility that some patients may experience this symptom, as individual responses to medications can vary considerably based on genetic factors, concurrent medications, and underlying health conditions
Agilent Technologies, Folsom, CA, USA)
77,78,79 For example, Golodirsen, an ASO drug targeting the human Duchenne muscular dystrophy (DMD) gene, was introduced in the USA in 2019 by Sarepta Therapeutics to treat DMD patients with confirmed mutations amenable to exon 53 skipping
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