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Stability considerations in experimental design If a substantial proportion of parent peptide converts to unidentified metabolites within an hour in plasma ex vivo, several design consequences follow: Time-course design matters considerably Single-timepoint measurements may miss the effect window entirely Analytical methods separating metabolites from parent compound give a very different picture to those that do not Effects in longer experiments may be attributable to metabolites rather than the parent molecule 5

Faster Wound Healing Speeds up tissue regeneration in muscles, ligaments, and tendons It may reduce scarring and enhance skin repair Used in post-surgical recovery 2

doi:10.1002/mas.21479

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