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Glucagon-like peptides 1 and 2 in health and disease: a review
A 2023 study published in JAMA Ophthalmology examined over 16,000 patients and found a small but statistically significant increased risk of certain retinal complications in those prescribed semaglutide compared to other diabetes medications
Experimental and human metabolic literature demonstrates that GH promotes fatty acid mobilization, shifts substrate preference toward fat oxidation, and alters carbohydrate-lipid partitioning during fasting and metabolic stress states, making GH secretagogue systems useful tools for investigating adipose tissue signaling, fuel selection, and the endocrine regulation of energy metabolism [8]
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