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If coverage remains unavailable, explore affordable tirzepatide options or compounded semaglutide as alternatives

Moreover, given no heterogeneous treatment effects found by age, gender, or diabetes severity for GLP-1RAs versus insulin in our previous analyses [6] and limited study subjects with different patient characteristics in the present study, performing the cost-effectiveness analysis stratified by different patient demographic or clinical characteristics would be infeasible

It is administered as a once-weekly subcutaneous injection with a defined dose-titration schedule

Among individual drugs, liraglutide has been noted to carry a relatively higher risk of nausea and vomiting