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Neuroendocrine normalization: Studies in aged animal models document normalized anterior pituitary function and restored luteinizing hormone and follicle-stimulating hormone pulsatility following administration

Therefore, our data suggest that inhibiting EndMT could be one of the potential mechanisms for the therapeutic effects of GLP-1 analogue on PH

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The oxygen of phenolic hydroxyl group in tyrosine residue is the proximal ligand of heme iron and is probably deprotonated with negative charge, so that it can lead to the stabilization of irons high oxidation states