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A 2025 preclinical study reported that Retatrutide-induced weight loss reduced tumor engraftment and progression in mouse models of obesity-associated pancreatic and lung cancer, alongside signs of immune system reprogramming

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Of greater clinical translational significance, RCTs have demonstrated that approximately 26 weeks of liraglutide treatment can significantly reduce hepatic fat content and improve transaminase levels, outperforming lifestyle interventions alone (79)

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Retatrutide is a synthetic peptide research compound also identified in scientific literature as LY3437943