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Robert C, Karaszewska B, Schachter J, et al
M., Goldberg, G
Gut incretin hormones in identical twins discordant for non-insulin-dependent diabetes mellitus (NIDDM)evidence for decreased glucagon-like peptide 1 secretion during oral glucose ingestion in NIDDM twins
These pathways play a crucial role in its wide-ranging therapeutic effects, extending the benefits of GLP-1RAs beyond metabolic diseases
Particularly, genes involved in lipid metabolism ( Abcg5 ), drug metabolism ( Cyp2a4 ), GSH metabolism ( Gstm2 and Gstm6 ), and oxidative phosphorylation ( Lhpp ) were expressed at higher levels in the liver of hepsin / mice compared with wild-type mice
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