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for instance, lighter skin became apparent after administering high doses for treating other diseases

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This can be due to viral infections (like dengue, hepatitis C), vitamin deficiencies (B12, folate), aplastic anemia, or as a side effect of chemotherapy and radiation

High epidemiological reliability denotes the strongest available evidence with no indication of significant variance or bias ( (i) Persuasive: statistical significance per the random-effects model of p 1,000 cases, low heterogeneity among the selected studies ( I 2 1,000 cases, and most studies indicating a significant effect

Signs include dizziness, blurred vision, anxiety, sweating, slurred speech, shakiness, confusion, a fast heartbeat or feeling jittery