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or ii) by one-way ANOVA followed by a KruskalWallis nonparametric test ( a )
Increased Risk of Pancreatitis Both medications carry a known, though rare, risk of inflammation of the pancreas (pancreatitis)
Studies indicate these medications can reduce markers like C-reactive protein and interleukin-6, potentially offering benefits beyond glucose management
Abbreviations ADVANCE: action in diabetes and vascular disease AMI: acute myocardial infarction BID: twice daily bpm: beats per minute CI: confidence interval CVOT: cardiovascular outcome trial ELIXA: Evaluation of LIXisenatide in Acute coronary syndrome FIGHT: Functional Impact of GLP-1 for Heart Failure Treatment GLP-1 RA: glucagon-like peptide-1 receptor agonist HF: heart failure HR: heart rate LAR: long-acting release LEADER: Liraglutide Effect and Action in Diabetes: Evaluation of Cardiovascular Outcome Results LIVE: Effect of LIraglutide on left VEntricular function in chronic heart failure patients with and without type 2 diabetes LS: least squares PK: pharmacokinetic QD: once daily QW: once weekly SE: standard error T2DM: type 2 diabetes mellitus References Inzucchi SE, Bergenstal RM, Buse JB, Diamant M, Ferrannini E, Nauck M, Peters AL, Tsapas A, Wender R, Matthews DR
The hormone has become more well-known as GLP-1 agonist and GLP1-GIP receptor medications, such as semaglutide (Ozempic, Wegovy) and tirzepatide (Mounjaro, Zepbound), have become prescribed more often
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