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P09488-2: 21253 Da (predicted)

A 30-year-old with no cancer history and no significant family history faces fundamentally different considerations than a 55-year-old with previous cancer or strong hereditary risk

used in this study were highly resistant to 30 mM GSH (Figure 1)

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Such a non-protein cofactor is known as a "prosthetic group." R -lipoic acid functions as a prosthetic group for the biological activity of the following multienzyme complexes: The glycine cleavage system that catalyzes the decarboxylation of glycine coupled with the addition of a methylene group (-CH 2 ) to tetrahydrofolate to form 5,10-methylene tetrahydrofolate, an important cofactor in the synthesis of nucleic acids ( Figure 3 )