With Tirzepatide removed from the drug shortage list, compounded alternatives are unauthorized, urging providers to adopt safer, compliant options
Muscle tissue, by contrast, has higher blood flow and different absorption kinetics that can accelerate medication entry into the systemic circulation
PMID: 40 van den AmeeleSFuchsDCoppensVde BoerPTimmersMSabbeBet al
Tirzepatide is administered as a once-weekly subcutaneous injection, with a recommended starting dose of 2.5 mg once weekly for 4 weeks, then increasing by 2.5 mg every 4 weeks until the target dose (up to 15 mg) is reached
Given the widespread and increasing use of these medications and the urgency of providing advice to individuals using the drugs, as well as calling for more research the researchers argue that we can turn to what has been learnt from the guidance and support offered alongside weight loss surgery, such as gastric bands, which leads to similar outcomes to GLP-1 drugs