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PMID: 147 AlaviMFarkhondehTAschnerMSamarghandianS

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When present, side effects are typically mild and may include vivid dreams or altered sleep architecture as the brain undergoes increased neuroplastic activity, mild headaches during initial therapy (often resolving within days), temporary changes in appetite, or subtle mood variations during the adaptation period

Patients with Crohns disease are usually under increased oxidative stress and have lower levels of antioxidant vitamins

Therefore, frequent medication adjustments are necessary at specific intervals to ensure that treatments remain effective