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The norleucine-4 modification eliminates the methionine residue susceptible to oxidation, while the D-phenylalanine-7 substitution enhances receptor binding affinity by constraining the peptide backbone in a conformation that favors MC1R interaction
J Breast Cancer 19:1825 Kim SH, Park HS, Hong MJ, Hur HJ, Kwon DY, Kim MS (2018) Caffeic acid phenethyl ester improves metabolic syndrome by activating PPAR-gamma and inducing adipose tissue remodeling in diet-induced obese mice
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Running out mid-protocol disrupts consistency
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