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10.1016/j.bbamem.2015.01.006 282

In diseases where amino-acid metabolizing enzymes are dysfunctional or absent (e.g., propionic acidemia and methylmalonic acidemias characterized by neurological symptoms, muscle weakness and low energy) C3 accumulates, and higher blood levels are used as a screening tool

Vegans and vegetarians are naturally at higher risk since B12 comes mainly from animal products

Its antioxidant and anti-inflammation effects are also useful when treating acne, rosacea, and hyperpigmentation

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