Kevin, an additional concern with GLP-1 drugs, and rapid weight loss in general, is muscle wasting , especially in people over 40
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A 2025 meta-analysis looked at five studies on GLP-1s for people with eating disorders and found that people with BED taking a GLP-1 showed a reduction in binge eating symptoms and lost significantly more weight compared to control groups
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Because the supplement aims to increase GLP-1 production, and GLP-1 directly affects insulin secretion and glucose metabolism, blood sugar levels can become less predictable during the adjustment period