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Intriguingly, some evidence suggests GLP-1RA usage may improve surgical complications, such as surgical site infections and wound healing
Given the previously observed cardioprotective actions of GLP-1 in the absence of the GLP-1R, these data suggest that the ex vivo heart may not effectively metabolize GLP-1 to GLP-1(2836)
The practical takeaway: it is not just how much Ipamorelin is administered but when and specifically how far from food and insulin that shapes the size of the GH pulse in the research framing
References Balderas-Vazquez CL, et al
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