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Synapsin is exclusively expressed in neurons, and confirmation of Gipr KO revealed that Gipr expression was lower in the brainstem, hypothalamus and hippocampus of Gipr Syn/ mice than in Gipr fl/fl control mice, while Gipr expression in pancreatic islets was similar between the two genotypes (Fig
For a 200-pound patient, that difference translates to roughly 12 additional pounds lost
For them, semaglutide is strictly a drug for losing pounds
Its approved for type 2 diabetes by the FDA, but some doctors may prescribe it off label for obesity
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