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The body cannot produce B12 independently, so it must be obtained through dietary sources or supplementation

There is no single correct amount more water simply spreads the same 5 mg of peptide across a larger volume, which makes small doses easier to measure accurately

In one published case, an active, lean-adjacent man lost about one-third of his total weight as muscle on 2.5 mg and recovered it after adding resistance training and increasing protein. This is a cautionary case, not an incidence estimate

It also depends on the frequency at which you get B12 shots

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