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Specialized nutrient-sensing cells respond to food intake by releasing peptide hormones into the circulation, which act either directly on the -cell, or indirectly via neural relays, and may account for 6070% of total insulin release in healthy human subjects [7, 12]
In a mouse model of LN, SGLT2i were shown to alleviate podocyte damage via mTORC1 and autophagy pathways7
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DOI: 10.14309/01.ajg.0001131868.76662.c6
LIPO-C is generally well-tolerated when administered correctly, but localised injection site reactions (redness, swelling, tenderness) occur in 1020% of patients during the first few weeks
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