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Nevertheless, when applied to stressed cortical neurons with reduced mitochondrial membrane potential, PBM returned the membrane potential to normal, thereby reducing ROS production and excitotoxic Ca 2+ levels (Huang et al., 2013, 2014), where the effects of PBM on mitochondrial function have been found to be both dose and time dependent (Silveira et al., 2019)

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Pentadecapeptide studied in cytoprotective and angiogenic research models BPC-157 is a 15-amino acid peptide fragment derived from human gastric juice

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