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D., Rush, P

Sustainable weight management is best achieved through a combination of dietary change, physical activity, and behavioural support, with pharmacotherapy used as an adjunct where clinically indicated and in line with NICE guidance

GHD also contributes to the alteration of body composition and weight gain, with decreased lean mass, increased FM, mainly truncal FM with increase waist/hip ratio, scarce muscle tone and strength, reduced energy expenditure, and exercise tolerance [45,46,47]

Historical Background and Scientific Context Scientific interest in synthetic peptides expanded substantially as advances in analytical chemistry and peptide synthesis enabled researchers to investigate increasingly complex molecular communication systems

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