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Direct head-to-head data does not yet exist, but the magnitude gap is large enough that most analysts consider retatrutide the more potent weight-loss compound

141 Furthermore, emerging evidence suggests that the gut microbiota may influence the development of DH through the modulation of metabolism and inflammation

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These medications are highly effective but come with a unique profile of adverse effects that affect multiple organ systems and present important considerations for emergency clinicians

A new signal: dysesthesia with retatrutide The TRIUMPH-4 Phase 3 trial revealed a side effect not previously highlighted in earlier data