The injection should be given in the middle third of both axes
Sterile, clear solution in a rubber-stopper laboratory solvent vial designed for repeated access with proper aseptic technique
In vivo murine MTB challenge experiments confirmed the protective efficacy conferred by metE when formulated as recombinant protein with AS01 or AddaS03 adjuvants, compared to the nave group
Side effects from B12 supplementation are uncommon but may include: Mild gastrointestinal symptoms such as nausea or diarrhoea, typically with very high oral doses Headache or dizziness in some individuals Skin reactions (rash, itching) at injection sites when using intramuscular preparations Rare but serious allergic reactions, including anaphylaxis with injectable forms Hypokalaemia (low potassium) may occur during rapid correction of severe megaloblastic anaemia If you experience symptoms of a severe allergic reaction (difficulty breathing, severe rash, swelling of face or throat) after taking B12, seek immediate medical attention
Many of the symptoms caused by low B12 levels are not specific to B12 deficiency, which can cause the condition to go undetected