You start at a high temperature, then a medium temperature, and go to a low temperature. But for something driven out of equilibrium, its not really true to say that the system has a temperature, and since thats the case you can have strange shortcuts. The thought-provoking work drew the interest of others, including a Spanish group that began simulating what are known as granular fluids collections of rigid particles that can flow like liquids, such as sand or seeds and showed that these, too, can have Mpemba-like effects
Thermospray liquid chromatography/mass spectrometry for the analysis of L-carnitine and its short-chain acyl derivatives
But overnight or longer at room temperature can compromise the peptide
Are GI side effects typically this severe
Injections add risks like bruising, swelling, pain, and infection from poor technique, so this route belongs in a clinic setting with sterile protocols