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NMs have been investigated for their genotoxic effects, immunomodulatory properties, and potential to induce fibrosis
Skin-depigmenting agent monobenzone induces potent T-cell autoimmunity toward pigmented cells by tyrosinase haptenation and melanosome autophagy
The combined effect of these modifications increase the drugs half-life from minutes to approximately 168 hours, enabling its once-weekly injection schedule an enormous improvement compared to the twice daily injection required for exenatide (Byetta) which was the first GLP-1 drug that was launched.1 Semaglutide (under the brand names Ozempic and Wegovy) swept the market
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