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In Summary Vitamin B12 (cyanocobalamin or cobalamin) is a crucial vitamin for many of the bodys everyday processes, and deficiencies can contribute to serious disease

NAD+ depletion during chronic inflammation can impair sirtuin activity, exacerbating inflammatory diseases like arthritis, diabetes, and heart disease

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Other proposed methods include advanced imaging modalities, such as anterior segment optical coherence tomography (AS-OCT), quantitative susceptibility mapping (QSM), and copper-64 positron emission tomography, which offer noninvasive tools for detecting early disease changes

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