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doi: 10.1242/jeb.01022 152 PunPBLLuJMoochhalaS
These observations suggest that SIRT1, through inhibition of the NLRP3 inflammasome, can mitigate PD neuropathology
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For instance, daily administration of a combination of vitamin E (1200 IU) and vitamin C (1000 mg) for eight weeks led to significant improvements in chronic pain, dysmenorrhea, and dyspareunia compared to placebo (164)
They also slow digestion by increasing the time it takes for food to leave the body
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