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Factors That Affect How Long B12 Stays in the Body Several factors influence how long B12 stays in the body, including health conditions, metabolism, and age
a 2025 IV pilot in two adults used 10 mg and 20 mg single infusions and reported no adverse effects (Lee et al., Alternative Therapies in Health and Medicine)
- [Retatrutide Phase 2 Trial Supplementary Appendix: Drug Preparation]( *New England Journal of Medicine*, 2023
Tiredness, stress, ill-health, poor or limited diet will all reduce this absorption further. For some people, taking a vitamin B12 supplement is one of the easiest ways to maintain healthy levels
Medication is one piece of the picture
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