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Description

For GLP-1R, G s coupling induces a significant outward movement of the extracellular portion of TM bundles (Supplementary Fig

This architecture creates an extraordinarily high binding affinity (pK = 16.44), roughly 10 million times stronger than other tripeptides and comparable to albumins copper binding

This means it sends signals to your brain, reducing your appetite and causing the stomach to empty more slowly, making you feel less hungry and fuller for longer