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Overall, these results demonstrate that GLP-1 RAs may exert their therapeutic effects through multiple mechanisms in MASH treatment
However, T2DM patients with a lower tolerability for GLP-1R agonists may prefer treatment with DPP-4 inhibitors for the management of hyperglycemia
The FDA-approved dose of tesamorelin (Egrifta) is 2 mg subcutaneously once daily for HIV-associated lipodystrophy
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