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No significant publication bias was detected (Supplementary Figure S10)
This drug has been shown to cause liver toxicity, and one of the mechanisms causing damage is the depletion of glutathione stores in the liver
SAM supplies methyl groups for hundreds of reactions involving DNA, phospholipids, neurotransmitter metabolism, creatine synthesis, hormone metabolism and selected detoxification reactions
doi:10.1146/annurev.biochem.77.032207.120833
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