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doi: 10.3390/ijms251810167 47 De JongeCBarrattCLR

& Nicotera, P

Instead of suppressing the immune response, svL4 repairs the structural defect that allows the immune response to perpetuate

These efforts seek to surmount limited transport across the BBB, intratumoral heterogeneity, treatment-limiting toxicities, and inadequate pharmacodynamic durability