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Inhibiting the transcriptional activity of Nrf2 can reduce glutathione synthesis

Reuter, S., Gupta, S

For the quantification of these metabolites in TIF samples, 5 l samples were extracted in 45 l ice-cold extraction solvent (75% acetonitrile, 25% methanol and 0.1% formic acid) containing isotope-labelled internal standards (36 M 13 C 2 , 15 N-GSH, 0.92 M 13 C 4 , 15 N 2 -GSSG and 10 M D 4 -cystine)

2022), nitrated fatty acids (Mata-Prez et al

Studies using rat incisional wound models demonstrated that BPC-157 treatment significantly increased tensile strength of healing tissue and improved collagen organization within the wound