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However, the regulatory status of research peptides remains complex, with most lacking approval for human therapeutic use

Compounds such as thalidomide and its analogs lenalidomide and pomalidomide promote interactions between E3 ligases (e.g., cereblon) and specific target proteins, triggering their ubiquitination and proteasomal degradation

[11] Two magnesium ions function to stabilize the acylphosphate intermediate, facilitate binding of ATP, and activate removal of phosphate group from ATP