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The drug repositioning activity is based on in vivo and in vitro tests

A., Wharton, S., & the STEP 5 Study Group

While most GLP-1-related headaches are mild and self-limiting, certain presentations require prompt medical evaluation

Journal of Endocrinology and Metabolism, 109 (2), 321-328

For example if it is injected for vertical lip lines caused by side sleeping, consider use of a side sleeping pillow to take pressure off the treatment area