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For instance, mouse models lacking gut microbiota exhibit diminished expression of occludin and claudin-5, along with increased BBB permeability [294]
Microbial diversity is fundamental to maintaining gut ecosystem homeostasis and overall host health, with its abundance and stability directly shaping the adaptability of the intestinal microecosystem and host physiological function
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A common approach is a short retention (e.g., a few minutes) with clinician guidance on frequency and duration
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