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Multiple uremic toxins have been identified as inducers of eryptosis, including indoxyl sulfate (IS) (Ahmed et al., 2013a), phosphate (Voelkl et al., 2013), acrolein (Ahmed et al., 2013b), vanadate (Fller et al., 2008b), and indole-3-acetic acid (IAA) (Gao et al., 2015) as listed in Table 1

Heres a breakdown of the two main mechanisms: 1

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