Increasing before steady state means you never truly experience the full effect of the current dose, and you stack side effects from rapid escalation on top of the natural adjustment period
FDA) Orange Book and those asserted in litigation (where applicable), statements made by companies in their SEC filings or in press releases, as well as journal articles that provided analysis of the drugs and related patent information to determine the expiry date for the primary patents on each drug
Of these, 43.5 per cent described at least one side effect
Jorsal A, Kistorp C, Holmager P et al (2017) Effect of liraglutide, a glucagon-like peptide-1 analogue, on left ventricular function in stable chronic heart failure patients with and without diabetes (LIVE)a multicentre, double-blind, randomised, placebo-controlled trial
doi:10.3389/fnut.2021.632469 Reding KW, Cain KC, Jarrett ME, Eugenio MD, Heitkemper MM