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Thereafter, we investigated the antischistosomal activity and ability of the antioxidants N -acetylcysteine (NAC) and resveratrol (RESV) to augment the performance of praziquantel and/or artesunate (AS) against larval stages of the parasite
TABLE 2 Body weights in different treatment groups
The FDA's 2003 guidance on pharmacokinetics in patients with impaired hepatic function acknowledges that drugs primarily cleared by non-hepatic mechanisms may not require dedicated hepatic impairment studies [5]
Since several studies document a decrease in adherence as therapeutic complexity increases, an improvement in therapeutic adherence can be expected with the use of this drug, especially considering the excellent results that patients can achieve in terms of weight reduction
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