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Superoxide reacts with NO and generates PNT (peroxynitrite), which nitrates T-cell receptors and limits the response of antigen-MHC complexes, thus suppressing T cells directly
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Notably, measurement of full doseresponse curves for all three ligands was necessary to quantify selectivity among library variants
A small bruise and/or soreness at the site are completely normal
In practice the compound is available in the UK only as a research chemical sold for in vitro and preclinical work, labelled 'for laboratory and research use only not for human consumption'
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