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However, abrupt discontinuation of GLP-1R agonists in patients with metabolic disorders may lead to rapid weight regain and potential exacerbation of IIH symptoms, as reported in a case study [101]
Model outputs included life-years (LYs), QALYs, and total and disaggregated costs (estimated in 2021 EUR)
Stress management is often overlooked but relevant, as stress can exacerbate gastrointestinal symptoms through the gut-brain axis
Microdosing offers a gentler alternative for specific populations but lacks formal research validation
Their characterization by electrophysiological approaches revealed that they are mostly closed under basal conditions and activated by different stimuli that are also known to induce eryptosis: ROS, exposure to high extracellular osmolarity, or removal of extracellular Cl - and isosmotic replacement with gluconate activate the channel [98] and trigger eryptosis [90]
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