l carnitine and synthroid does interfere with The Complex Web of Interferences Thyroid Function Tests Role of carnitine in disease – How Does Carnitine Support Hashimoto's?

9% use it for 45+ days[] These safe therapeutic doses can significantly deplete glutathione in women who already have low baseline levels.[] Healthy individuals can tolerate up to 4g/day with only modest glutathione decrease, but individuals with compromised glutathione experience significant depletion even at therapeutic doses

Patel YC, Wheatley T, Zingg HH

The identification of predictive biomarkers could further optimize these combination strategies (114, 115)

Theres no strong clinical evidence favoring one time over the other

Reduced caloric intake from tirzepatide plus enhanced fat mobilization from AOD 9604 creates a significant metabolic shift that the body needs time to adapt to