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It is recommended to prioritize its use in patients with comorbid ASCVD or CKD
Risks of compounded GLP-1s include: Improper prescriptions Dosing errors Lack of standardization Contamination Misbranding of products The FDA is currently concerned with an increase in cases of unapproved compounded semaglutide and tirzepatide marketed in the U.S., encouraging consumers to be cautious of where they are getting their medications from
Current FDA Status (January 2026) Retatrutide is currently an investigational new drug (IND)
That's a big change in how much you're eating, and it can create gaps in your nutrition
Constipation: In some cases, this can lead to more severe intestinal blockages or fecal impaction
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